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Besides, rates of ice crystal growth in regular saline added with trehalose are slow compared to those in normal saline with l-proline at the exact same concentrations. These outcomes declare that both trehalose and l-proline can become CPAs by preventing eutectic development and inhibiting ice formation in typical saline for cellular cryopreservation. It can be useful for CPA selection and creating as time goes on. Chronic lymphocytic leukemia (CLL) is the most common leukemia among grownups. The prognosis of CLL patients varies