https://www.selleckchem.com/products/GDC-0449.html
As compared to the published data on PK of pdFIX, Kedrion FIX displayed a longer half-life (22.37-55.73hrs), reduced clearance, and regular volume of distribution at PK I by both NCA and OCM. The comparison of outcomes of PK II with those of PK I by OCM, also showed significant changes, particularly in patients on prophylaxis, who showed some improved parameters of PK. Due to two outlier values at the end of the trial, the NCA parameters of PK I were not compared to those of PK II. Breakthrough bleeds were successfully treated with 1 o
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