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The proposed method is highly sensitive and selective and is thus particularly useful for fast and simple clinical diagnosis of diseases, such as Alzheimer's disease and cardiovascular disease.A versatile strategy, based on the use of an amphiphilic copolymer as a macromonomer, was developed for the preparation of a fully synthetic MIP (molecularly imprinted polymer) sensor for protein recognition. A UV-crosslinkable copolymer poly(DMA-co-HEA-co-St) (UPDHS) was designed and synthesized to assemble with the template protein in aqueous solu