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Humans show a spectrum of sodium-sensitivity, with some people showing an important blood circulation pressure increase in response to increased sodium intake while other individuals experience very little change. These distinctions are, in part, owing to hereditary variation in pathways associated with salt maneuvering and removal. ENaC (epithelial sodium channel) is amongst the key transporters responsible when it comes to reabsorption of salt when you look at the distal nephron. This stati
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