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Herein, we indicate a first-of-its-kind novel point-of-care unit that utilizes an original strategy by directly keeping track of a panel of five cytokine biomarkers (IL-6, IL-8, IL-10, TRAIL IP-1, that is attributed as an indication of the body's number immune response to sepsis. The developed point-of-care device encompasses a disposable sensor cartridge mounted on an electrochemical reader. High susceptibility is attained owing to the initial sensor design with a range of nanofilm sem