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We additionally monitored the CSF IL-10 degrees of the 10 newly identified PCNSL patients. In seven newly identified PCNSL patients with adequate standard CSF cfDNA, six had ≥1 mutated genetics in their particular CSF cfDNA. The most typical had been MYD88(4/7), PIM1(3/7), MLL2(3/7), and ETV6(2/7). We also identified several somatic mutations, most often in PIM1. MYD88L265P could be recognized both in tumor tissue and CSF cfDNA. The genomic profiles of CFS cfDNA had been s
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