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0073). Seventy-seven patients had follow-up testing approximately 1 year after enrolment and 11/28 (39%) patients had persistently positive IgM. CONCLUSION Further studies are needed to better understand the natural history of parvovirus B19 infection in SCD especially in relation to RBC transfusion as a risk factor, as well as disease outcome and severity. © 2020 British Blood Transfusion Society.Aging is a natural biological process in living organisms characterized by receding bioenergetics. Mitochondria are crucial for cellular bioen