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The impact of alcohol use among adolescents is multidisciplinary and affects the adolescent's academic performance, precipitates with sexually transmitted infections or psychiatric disorders, and disturbs the social domain of adolescents. Therefore, this study aimed to assess the prevalence and associated factors of alcohol use among adolescents aged 15-19 years at the governmental high schools of Aksum Town, Tigray, Ethiopia, in 2019. A facility-based cross-sectional study was conducted from 1 to 30 January 2019 at Aksum town high sc