https://www.selleckchem.com/pr....oducts/ro-61-8048.ht
Protein structure modeling via I-TASSER revealed different folding patterns between the two species' Y-proteins, and functional predictions via TreeSAAP further reveal physicochemical differences as a result of non-synonymous substitutions. These differences inform our understanding of the evolution of primate Y-proteins involved in spermatogenesis and, in turn, have biomedical implications for human male fertility. Colitis is a significant complication of immune checkpoint inhibitors (ICI). Currently, clinical and endoscopic severit