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This work represents the first example of electride-sponsored radical-controlled CO 2 reduction, and thus provides an alternative strategy in the exploration of the CO 2 conversion. © 2020 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim.BACKGROUND Tacrolimus is a calcineurin inhibitor commonly used for prophylaxis of rejection in renal and liver transplantation. There are limited but favourable data regarding its possible use in patients with inflammatory bowel disease (IBD). AIMS To evaluate the efficacy and safety of tacrolimus in pati