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ADHD Medications For Adults Stimulants can help regulate levels of chemical messengers in the brain, which control attention. They are considered to be the first line of treatment for ADHD. They aren't considered to be habit-forming, but they can have negative side effects, including headache and trouble sleeping. Your doctor could also prescribe guanfacine (brand names Tenex and Intuniv) or clonidine (Catapres) to decrease hyperactivity and impulsivity. These medications ha