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This study focuses on optical nanosensors based on constant-wavelength synchronous fluorescence spectroscopy (SFS) and reviews their applications for analysis purposes in the last few decades. In comparison to conventional fluorescence, SFS shows a higher selectivity owing to the narrowing of spectral bands and the simplification of spectra. The reported SFS-based nanosensors are classified based on their mechanism for analyte detection into two types including quenching based methods and enhancement based methods. Herein, almost all studi
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