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What Happens If ADHD is Left Untreated in Adults? Untreated ADHD can lead to a myriad of issues for adults. These can include issues with work, relationships and mental health. Adults who suffer from untreated ADHD generally have low self-esteem, and an unfavorable view of the world. This can make them feel as if they're failing at work and at home. Lack of Focus Being unable to focus from time to time is normal, especially after a long day at school or at work. If you notice that your ability to concentrate is de