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To describe the clinical presentation, management, and visual outcomes of 6 eyes with endophthalmitis after Descemet stripping endothelial keratoplasty (DSEK). Retrospective case series. Setting Tertiary, academic eye center. StudyPopulation Individuals developing endophthalmitis after DSEK at the Duke Eye Center from January 1, 2009, to January 1, 2018, with at least 6months of follow-up. ObservationProcedure Retrospective chart review. OutcomeMeasures Diagnostic procedures, microbiological yield, and visual outcomes. Six eyes of 6 pat