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Liquor usage disorder (AUD) frequently co-occurs along with other health issues or any other material use, complicating our knowledge of the health-related standard of living (HRQoL) of AUD. We described the HRQoL of alcohol usage disorder into the presence of co-occurring problems and identified the contribution of each. Secondary analysis of National Epidemiologic study on Alcohol and Related Conditions III information, comprising 36,309 non-institutionalized US adults; descriptive and regression