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PURPOSE This study describes the development and validation of an age-appropriate website for preschool children who require clean intermittent catheterization (CIC). METHODS An age-appropriate website was developed at an academic medical center in Brazil and included child-friendly characters, details of the urinary system anatomy and physiology, hand-washing, and the CIC procedure. Content was validated by physicians, nurses, and health informatics professionals. Face validity was assessed by parents. FINDINGS Content and face validity indices were 0.94 a