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ADHD Medications - Stimulant Or Non Stimulant? For a lot of people, stimulant medications are the first option for treating ADHD. However, for some, they cause side effects or don't help. Some doctors prescribe stimulants in addition to non-stimulant ADHD medication. These include medicines that treat high blood-pressure like clonidine or Guanfacine (Tenex). They also include other medications that help to increase wakefulness. Benefits Stimulants are the first medication do