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The osteoblast-derived polypeptide, osteocalcin (OC), has been associated with lower risk of type 2 diabetes and metabolic syndrome (MetS) in several epidemiological studies. Animal studies indicated the undercarboxylated form of osteocalcin drives its association with metabolic outcomes. We compared associations of undercarboxylated and carboxylated OC with MetS and its components in older men. A cross-sectional analysis of 2575 men aged 70 resident in Perth, Western Australia. Undercarboxylated osteocalcin (ucOC) was assayed using