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ADHD in Adult Women Treatment ADHD symptoms can be made worse by hormonal fluctuations. They can increase when ovulating, or at other times during the menstrual cycle. They can also fluctuate from day to day based on the hormone levels. Women and girls often have more subtle symptoms than men or boys and are less likely to be diagnosed. The disorder can have a serious impact on their lives. Medications Women with ADHD tend to have a harder time getting diagnosed and treated than men.