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Prostate cancer is a malignant disease that severely affects thehealth and comfort of themale population. The long non-coding RNA TP73-AS1 has been shown to be involved in the malignant transformation of various human cancers. However, whether TP73-AS1 contributes toprostate cancer progression has not been reported yet. Accordingly, here weaimed to report the role of TP73-AS1 in the development and progression of prostate cancer and determine its relationship with TP73. TP73-AS1-specific siRNA oligo duplexes were used to silence TP73-AS1