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Copyright © 2020 Yarmarkovich, Farrel, Sison, di Marco, Raman, Parris, Monos, Lee, Stevanovic and Maris.Actinomycete bacteria from marine environments represent a potential source for new antibiotics and anti-tumor drugs. Ten strains belonging to the genus Streptomyces isolated from the marine sponge Antho dichotoma collected at the bottom of the Trondheim fjord (Norway) were screened for antibiotic activity. Since only few isolates proved to be bioactive in the conditions tested, we decided to gain an insight into the