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ADHD Medication - Choosing the Right One Medicines can be an essential part of treatment for ADHD. Different medications affect everyone differently, and finding the right one may take time. Stimulants increase levels of brain chemicals which aid in controlling impulses and focusing. They can also cause negative side effects, such as shaking hands, stomach aches and an increase in heart rate. Stimulants Stimulants are drugs that enhance -- or "stimulate" -- activities and processes i