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SGLT-2i separately. Registration URL https//www.clinicaltrials.gov. Unique identifier NCT03878706.Innate immune activation has been attributed a key role in traumatic brain injury (TBI) and successive morbidity. In mild TBI, however, the extent and persistence of innate immune activation are unknown. We aimed to determine plasma cytokine level (1) changes over 12-months after a mild TBI in hospitalized and non-hospitalized patients compared to community controls; and (2) associations to injury-related and demographic variables at admiss