https://www.selleckchem.com/pr....oducts/BIX-02189.htm
Similar intracellular APP staining was observed in the cerebellum and cerebrum of AD mice at 2 to 10months. Similar expression of full-length APP and C-terminal fragments were indicated in the cerebrum and cerebellum of AD mice during aging. Our study in post-mortem human brains and transgenic AD mice provided neuropathological and functional evidence that cerebellar dysfunction may occur at the early stage of AD and likely independent of Aβ plaque. Our study in post-mortem human brains and transgenic AD mice provided neuropathologica
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