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Developing evidence shows that apoptosis-signal regulating kinase 1 (ASK1) is triggered in oxidative anxiety, which in turn causes hepatic swelling and apoptosis, leading to liver fibrogenesis through a mitogen-activated protein kinase (MAPK) downstream signals. In this study, we investigated whether selonsertib, a selective inhibitor of ASK1, reveals healing efficacy for liver fibrosis, and elucidated its procedure of activity in vivo plus in vitro. Because of this, se