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224-5p level were both associated with better prognosis. Moreover, high miR-1224-5p level was an independent prognosis factor for GBM patients according to the cox regression analysis. MiRNA-1224-5p could be a potential target for the prognosis and treatment in GBM. MiRNA-1224-5p could be a potential target for the prognosis and treatment in GBM. Lianhuaqingwen and Shuanghuanglian are drug treatment options for Corona Virus Disease 2019 (COVID-19). In China, use of traditional Chinese medicine with Shuanghuanglian or Lianhuaqingwen (fo