https://www.selleckchem.com/pr....oducts/Cyclopamine.h
Human serum albumin (HSA), which is distributed throughout the blood, is used as a carrier for transporting drugs to tumors based on the enhanced permeability and retention (EPR) effect. To develop an agent for the in vivo radiolabeling of endogenous albumin, we designed and synthesized novel hydroxamamide (Ham)-based technetium-99m (99mTc) complexes, which contained a monovalent or bivalent 4-(4-iodophenyl)butyric acid (IA) derivative as an albumin binder (AL moiety ([99mTc]AB2 and [99mTc]ALB2, respectively), and evaluated their
Like
Comment
Share
