https://www.selleckchem.com/pr....oducts/1-deoxynojiri
The development of non-invasive pharmacological therapies to prevent the progression and rupture of intracranial aneurysms (IA) is an important field of research. This study attempts to reveal the role of BP-1-102, an oral bioavailable STAT3 inhibitor, in IA. We first constructed an IA mouse model by injecting elastase into the cerebrospinal fluid with simultaneous induction of hypertension by deoxycorticosterone acetate (DOCA) implantation. The results showed that the proportion of IA rupture in mice after BP-1-102 administr
Like
Comment
Share
