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Finding the Best ADHD Medication For Adults Many adult ADHD treatment plans are based on medications. Finding the right dosage and medication is not always easy. Stimulants: These medicines can be used to treat hyperactivity as well as inattention. They work by increasing levels of the chemicals that transmit messages between nerve cells. They are taken multiple times a day and begin working in less than one hour. Stimulants Most doctors begin with stimulants to treat ADHD. Thes