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Mechanistically, Klf5 deacetylation activates Notch signaling. Klf5 and its own acetylation thus play a role in postnatal prostate development and regeneration by controlling basal progenitor cell fate.Node positive mind and throat squamous cellular carcinomas (HNSCCs) clients exhibit worse outcomes in terms of regional neck control, risk for remote metastases and overall survival. Smaller non-palpable lymph nodes can be inflammatory or may