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59, 95% CI 1.38-1.83, p = 0%). Moreover, a dose-response model indicated a significant positive association between WC and risk of liver cancer (exp(b) = 1.018, p less then 0.001). Conclusions This systematic review and dose-response meta-analysis highlights WC as a significant risk factor related to the incidence of liver cancer. Copyright © 2019 by S. Karger AG, Basel.Aim Ultrasound-guided fine-needle aspiration biopsy (FNA is a reliable, minimally invasive diagnostic method with high sensitivity and specificity in the evaluation