https://www.selleckchem.com/pr....oducts/epacadostat-i
This review will discuss the recent studies that implicate disturbed diurnal rhythms with the development of obesity. The second part of the review will discuss studies that use feeding time to restore diurnal rhythms and rescue obesity. Studies in patients with obesity and diabetes reveal attenuated circadian and metabolic rhythms in adipose tissue. The use of animal models furthers our mechanistic insight on how environmental disturbances such as high-fat diet and shift work disturb circadian and metabolic rhythms. Stud
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