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The goal of the current numerical simulation is to explore the impact of aspect ratio, thermal radiation, and entropy generation on buoyant induced convection in a rectangular box filled with Casson fluid. The vertical boundaries of the box are maintained with different constant thermal distribution. Thermal insulation is executed on horizontal boundaries. The solution is obtained by a finite volume-based iterative method. The results are explored over a range of radiation parameter, Casson fluid parameter, aspect ratio, and Grashof num