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Adult ADHD and Comorbid Disorders Many people with ADHD have comorbid disorders such as major depression (Kessler and colleagues, 2006). Many depressed patients aren't able to take medication and could get better results from therapy. Neurotransmitters are brain chemicals that regulate and boost levels of certain brain chemicals. The most commonly prescribed stimulants are amphetamine, methylphenidate and similar drugs. Medicin