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METHODS Serum from 75 RP patients who had been tested for mutations in a panel of 83 RP genetics and 73 normal settings, all aged 50-80 years, were screened for anti-recoverin antibodies by Western blot making use of recombinant recoverin, retinal lysate from a marmoset and commercial anti-recoverin antibodies as a control. RESULTS Three RP patients with typical pigmentary deterioration regarding the 75 (4.0%) were seropositive for anti-recoverin antibody. Pathogenic m