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Of these, 34 (22%) were performed for burn reconstruction in 25 patients (21%) with an overall higher 1-year mortality rate (12.0% versus 1.1%, P = 0.03. Of these deaths, 75% received 3 or more simultaneous allografts. Additionally, more episodes of acute rejection occurred compared to non-burn patients (4.4 versus 2.4, P = 0.035). Vascularized composite allotransplantation performed for burn reconstruction was found to be associated with a greater risk of 1-year mortality and nearly twice the number of episodes of acute rejection. F
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