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BACKGROUND The Centers for Medicare Medicaid Services (CMS) is the single largest payer for health care in the United States and the largest payer by spending globally. Medicare Part B, with more than 50 million beneficiaries, currently has no broad mechanisms in place for promoting cost-effective care of injectable drugs. OBJECTIVE To conduct a real-world utilization and cost analysis comparing botulinum toxins in movement disorders. METHODS The 2017 Medicare Provider Utilization and Payment Data Physician and Other