https://www.selleckchem.com/pr....oducts/nexturastat-a
21), while an effect size for abstinence could not be calculated. There were medium effects of topiramate on continuous measures of percent heavy drinking days (d=0.49) and alcohol-related problems (d=0.41). Topiramate is an efficacious pharmacotherapy for AUD. Although continuous measures of drinking and alcohol-related problems yielded larger effect sizes than the WHO RDLs, the latter nonetheless provide a categorical alternative for use in both clinical care and pharmacotherapy trials. Topiramate is an efficacious pharmacothera
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