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s the 1FED as first-line dietary treatment. This study aimed to clarify the effects of underlying diseases on clinical outcomes of patients aboard a world cruise ship. This prospective cohort study included patients who sought physician consultations at an onboard clinic on a 105-day world cruise (September-December 201X) on a ship chartered by a Japanese travel agency. Multivariable logistic regression analysis was performed to ascertain whether any concurrent disease, such as hypertension, was associated with additional onboard treatme