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In contrast to the IR team, modern speed treadmill instruction substantially paid off the appearance of NFκB, NLRP3, NEK7, ASC, pro-Caspase-1, GSDMD, GSDMD-N, IL-1β, and IL-18 when you look at the hippocampus of mice with IR. These results suggested 12-week modern rate treadmill machine education can substantially lessen the appearance of pyroptosis-related proteins and inflammatory factors in the hippocampus of mice with IR, and inhibit pyroptosis.The paper ended up being aimed to explore the role of serum exosomes caused by
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