https://www.selleckchem.com/pr....oducts/CI-1040-(PD18
To evaluate an influence of intracerebral L-lactate concentration on sleep-wake cycle. Twenty adult male white rats preliminary implanted (under general anesthesia) with the electrodes for neocortical EEG and a single cannula to a lateral ventricle were used as subjects. A 5 µl bolus of either saline or a solution of sodium L- or D-lactate (0.1 mg, 0.2 M, Sigma-Aldrich) was injected through the cannula and followed by a 6-hr recording. of L-lactate does not influence sleep-wake cycle of experimental animals. At the same time,