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athways,reducing the transcription of nuclear factor-kappaB( NF-κ,and inhibiting the secretion of intestinal inflammatory factors IL-1 and IL-6.The aim of this paper was to explore the effects of triptolide( TP),the effective component of Tripterygium wilfordii on improving podocyte epithelial-mesenchymal transition( EMT) induced by high glucose( HG),based on the regulative mechanisms of Nod-like receptor protein 3( NLRP 3) inflammasome in the kidney of diabetic kidney disease( DKD). The immortalized podocytes of mice in vitro were