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ADHD Medication For Adults UK The use of medication can reduce symptoms and make tasks easier. They can also aid in problems that are underlying, such as insomnia, anxiety, and depression. Adults with ADHD are treated first by stimulants (methylphenidate or the more recent amphetamine-based medication Lisdexamfetamine). They boost the levels of two chemical messengers in the brain that improve focus and decrease hyperactivity and impulsivity. Stimulants Stimulants boost the amount of neurotransmitters in the brain