https://www.selleckchem.com/pr....oducts/Fedratinib-SA
Organic acids commonly have quite symmetrical chromatography profiles at low pH ( less then 1.5) with strong anionic resins, but a significant tailing can be observed with succinic and citric acids. Classical adsorption models, like the Langmuir model, fail to predict this behavior, which can have a major influence on mean retention times and profile shapes, therefore on chromatography performances. A new retention model was developed to better predict organic acid separation with strong anionic resin. This model c