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This work presents an example of RNA domain modularity comparable to that of a ligand-binding protein, showcasing the versatility of RNA as an entity capable of molecular evolution through adaptation of existing motifs.Long-term monitoring of organic pollutants in the soil is a major environmental challenge. We propose to meet this issue by the development of a polymer dedicated to selectively react with H2S, coating surface acoustic wave transducers designed as passive cooperative targets with the compound, and probing their response u