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The present study determined the efficacy of a BU extract to deal with hepatocellular carcinoma (HCC) in rats in vivo and established its anti-angiogenic and anti-proliferative properties. The BU herb had been ready in 95% ethanol as well as its composition determined utilizing liquid chromatography-mass spectrometry. HCC was caused in Wistar rats by an injection of diethylnitrosamine (DEN), observed two weeks later on by injections of thioacetamide (TAA) thrice weekly for 30 days. Following 2 months, the