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The sensitivity, accuracy, and negative predictive value of ultrasonography combined with CT were 92.05%, 90.48% and 92.78%, retrospectively, which were significantly improved compared with those in the individual tests (x2=13.41, 6.126, 8.933, p=0.001, 0.047, 0.011), with significant statistical difference. Color Doppler ultrasound combined with CT examination can significantly improve the detected rate of axillary lymph node metastasis in breast cancer before surgery, and provide a reliable basis for the treatment options on breast can