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Prioritisation of elderly people in COVID-19 vaccination campaigns aimed at reducing severe outcomes in this group. Using EU/EEA surveillance and vaccination uptake, we estimated the risk ratio of case, hospitalisation and death notifications in people 80 years and older compared with 25-59-year-olds. Highest impact was observed for full vaccination uptake 80% or higher with reductions in notification rates of cases up to 65% (IRR 0.35; 95% CI 0.13-0.99), hospitalisations up to 78% (IRR 0.22; 95% CI 0.13-0.37) and deaths up to 84% (IRR