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72, 95% CI 3.18-7.01) and steroid usage (OR = 2.19, 95% CI 1.57-3.07), while there was no significant association between immunotherapy or hormonal therapy and seroconversion after vaccination. Subgroup analyses showed therapies with anti-CD20 antibody (OR = 11.28, 95% CI 6.40-19.9, B-cell lymphoma 2 inhibitor (OR = 5.76, 95% CI 3.64-9.1, and Bruton tyrosine kinase inhibitor (OR = 6.86, 95% CI 4.23-11.15) were significantly correlated with the risk of negative humoral response to vaccination. In conclusion, our results demonstrated
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