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81±81.3 μm versus (233.79±38.29) μm, p 0.05]. Multivariable regression analysis indicated that the ADAS-cog scores (β=-0.772, p = 0.00 and age (β=-0.176, p = 0.015) were independently associated with choroidal thickness. The logistic regression model revealed that the subfoveal choroidal thickness was a significant predictor for AD (OR = 0.984, 95% CI 0.972-0.997). There was a general tendency of choroid thinning as the cognitive function declined. Although choroidal thickness was not a potential indicator for early stage AD,